South Park

South Park is the most fearless show in television history. Trey Parker and Matt Stone built an empire on construction-paper animation and a willingness to attack every sacred cow in American culture with equal ferocity. The show's six-day production cycle means it can respond to current events faster than any other scripted series — an episode about a presidential election can air the night after the results come in. 'Scott Tenorman Must Die,' 'Make Love, Not Warcraft,' and the 'Imaginationland' trilogy are among the greatest episodes in comedy history. South Park's refusal to spare anyone has made it the most honest satirical voice on television for nearly three decades.